Submicroscopic structure of Yoshida ascites hepatoma.

Some ultrastructural features of Yoshida ascites hepatoma.

A comparative electron microscopic study on Ehrlich ascites tumor cells, Yoshida sarcoma cells, and human cancerous peritonitis ascites cells.

It is known that the Ehrlich ascites tumor is of epithelial origin, while the Yoshida sarcoma originates from the reticuloendothelium (13). The present paper deals with a comparative electron microscopic study of uninfected Ehrlich mouse ascites tumor (EAT) cells, Yoshida sarcoma (YS) cells, and human cancerous peritonitis ascites (HCPA) cells. A morphological analysis of the EAT by electron mi...

Metabolic-independent volume changes and Mg++ binding in mitochondria isolated from AH-130 Yoshida ascites hepatoma.

The mitochondria isolated in isotonic sucrose from AH-130 Yoshida ascites hepatoma appear spontaneously swollen (11, 12). This spontaneous swelling may be in part responsible for the inability of tumor mitochondria to undergo extensive volume changes in hypotonie conditions or in conditions that induce large-amplitude, metabolic-dependent, or metabolic-independent swelling in normal liver mitoc...

Marked hyperlipidaemia in rats bearing the Yoshida AH-130 ascites hepatoma.

Malignant tumour burden is a pathological s ta te associated with a considerable demand for nutrients by the growing tumour [l]. Although a great deal of work has been carried out, there are contradictory results about the effects of tumour burden on lipid metabolism both in experimental animals and man. Lipid oxidation has been reported either increased [2], unchanged [3] or decreased [4]. In ...

Carcinostatic effect of aliphatic aldehydes and aldehyde dehydrogenase activity in Ehrlich carcinoma, Sarcoma 180, and Yoshida AH 130 hepatoma.

The antitumor activity of 2,3-dihydroxybutyraldehyde on Ehrlich carcinoma, Sarcoma 180, and Yoshida AH 130 hepatoma, as well as the aldehyde dehydrogenase activity in these tumors, was studied. 2,3-Dihydroxybutyraldehyde at nontoxic doses (500 mg/kg body weight i.p. daily for 7 days) slowed down the growth of solid and ascites tumors in mice. The treatment completely prevented the development o...